Etude des oxydes transparents conducteurs pour l'amélioration de la sensibilité de biocapteur optique

Abstract

Over the two decades, surface plasmon resonance (SPR) sensors have gained great attention in the biomedical field for its unique properties, which can be used for various applications, such as biomedical diagnosis and prognosis, food safety,monitoring of environment drug development and label-free detection. It is a proven technique, very sensitive and reliable. The first advantage of the SPR technique is that it can detect minor changes in the refractive index (IR) of the dielectric medium (order of 10-7). Researchers are currently focusing on conductive and extremely ultrathin metal oxides with a high refractive index due to their excellent optical and electrical properties, such as zinc oxide (ZnO), titanium dioxide (TiO2), Silicon (SiO2) and indium tin oxide (ITO) for the adhesive layer are used as an adhesion layer between the prism glass and the metal layer. In order to improve the performance of biosensors with TCOs, an SPR-based biosensor with ZnO, TiO2 and SiO2is therefore proposed, this sensor can be used to detect biological activity or chemical reactions in the near infrared region.