Étude expérimentale et théorique des propriétés biologiques et inhibitrices de corrosion d’une nouvelle série de dérivés hydrazone.

Abstract

This thorough investigation explores the synthesis,characterisation,and detailed analysis of four different hydrazone derivatives. Compounds with distinct chemical structures were obtained from the synthesis by following published protocols from the literature.In order to learn more about the characteristics and possible uses of these hydrazone derivatives,theoretical investigations with Gaussian 09 offered quantum insights into the hydrazone derivatives, including electronic characteristics. VEDA program was utilized to investigate vibrational behavior and potential energy distribution (PED). Moreover,reactivity and bond nature features were revealed by topological analyses utilizing the Multiwfn program, MHZN was selected for corrosion research due to its distinct acid-soluble nature.Its Langmuir-type inhibitory model was demonstrated by adsorption isotherm studies and electrochemical testing such as Tafel analysis and EIS.The antioxidant activity of the four hydraeones was evaluated using DPPH method. the mechanism of action was determined via thermodynamic parameters Additionally Molecular docking studies via iGEMDOCK assessed the hydrazone derivatives' potential as antioxidants through interactions with the NADPH oxidase receptor, The effectiveness against four types of bactria was assessed in addition to molecular docking. This comprehensive strategy combines.synthesis, practical assessments,and analysis improves our understanding of hydrazone derivatives and lays the groundwork for a variety of applications in materials science and corrosion prevention.