http://dspace.univ-setif.dz:8888/jspui/handle/123456789/1414 2026-05-12T01:48:03Z http://dspace.univ-setif.dz:8888/jspui/handle/123456789/6596 Titre: IMMUNOLOGY : Course intended for L2 Biology Auteur(s): KHITHER, Hanane Résumé: Immunology is the branch of biology that studies the functioning of the immune system in both physiological and pathological contexts. It enables the investigation of the properties of immune effectors and their targets both in vivo and in vitro. The immune system comprises organs, tissues, cells (such as T and B lymphocytes, macro- phages, and leukocytes), and molecules (including antibodies and interleukins) that partici- pate in immunity. Lymphoid organs and tissues are distributed throughout the body. Immune cells circulate within and between these organs via blood and lymph. They communicate either through direct contact (receptor–ligand interactions) or at a distance via secreted molecules (media- tor–receptor interactions). These soluble, secreted molecules are called cytokines substances produced by certain immune cells that act on other immune cells to regulate their activity. This general term encompasses lymphokines, monokines, chemokines, and interleukins. 2025-01-01T00:00:00Z http://dspace.univ-setif.dz:8888/jspui/handle/123456789/5122 Titre: المقتنيات الجديدة لمكتبة كلية علوم الطبيعة والحياة 2024 Auteur(s): بن ستيتي , عبد المالك 2024-01-01T00:00:00Z http://dspace.univ-setif.dz:8888/jspui/handle/123456789/3069 Titre: COMPARATIVE STUDY: THE ANTIBACTERIAL ACTIVITY OF MELISSA IN RELATIONS TO OTHER PLANTS IN THE REGION OF SETIF, ALGERIA Auteur(s): Adimi, L. Z.; Guechi, A; Laidoudi, O; Chelil, S; Kicheh, I Résumé: Antibacterial properties of essential oils, hydro ethanoicextracts, and aqueous bactericidal extracts of four medical plants, known for their therapeutic effects: Melissa officinalis , Origanum vulgare , Lavandula angustifolia and Mentha piperita. The last three are largely used in Algeria; however, Melissa appears to be less famous. The following work has been executed in a laboratory for the purpose of, yet again, revealing and confirming the benefits of Melissa, and comparing it to other plants. Two microorganisms have been used: Escherichia coli and Staphylococcus aureus. Using the method of Aromatogram with essential oils, Melissa was active the most with zones of inhibition of 8 mm for Escherichia coli and 7 mm for Staphylococcus aureus. Applying the same method for hydro ethanoicextracts, Melissa was effective the most with a 50 mm zone of inhibition for Escherichia coli, followed by mint (40 mm zone of inhibition). As for Staphylococcus aureus, Melissa presented a 14 mm zone of inhibition, while mint displayed a zone of inhibition of 13 mm. Using the bioassay method with essential oils, Melissa has the best effect with a 40 mm zone of inhibition for Escherichia coli and 35mm for Staphylococcus aureus. Always with the same technique but with hydro ethanoicextracts, both Melissa and Mint presented the best inhibition value of 50 mm for Escherichia coli. As for Staphylococcus aureus, Melissa presented a 26 mm zone of inhibition, followed by mint with 24 mm. For the spectrophotometry technique, almost all four plants, witht heir aqueous extracts, presented a antibacterial activity for both bacteria. These results confirm the strong anti- bacterial and bactericidal activity of the four plants, especially Melissa, and their diverse traditional use. 2019-01-16T00:00:00Z http://dspace.univ-setif.dz:8888/jspui/handle/123456789/3004 Titre: Preussilides A−F, Bicyclic Polyketides from the Endophytic Fungus Preussia similiswith Antiproliferative Activity Auteur(s): Noumeur, Sara R.; E. Helaly, Soleiman; Jansen, Rolf; Gereke, Marcus; Stradal, Theresia E. B; Harzallah, Daoud; Stadler, Marc Résumé: Six novel bioactive bicyclic polyketides (1−6) were isolated from cultures of an endophytic fungus of the medicinal plantGlobularia alypumcollected in Batna, Algeria. The producer organism was identified asPreussia similisusing morphological and molecular phylogenetic methods. The structures of metabolites1−6, for which the trivial names preussilides A−F are proposed, were elucidated using a combination of spectral methods, including extensive 2D NMR spectroscopy, high-resolution mass spectrometry, and CD spectroscopy. Preussilides were tested for antimicrobial and antiproliferative effects, and, in particular, compounds 1and3showed selective activities against eukaryotes. Subsequent studies on the influence of1and3 on the morphology of human osteosarcoma cells (U2OS) suggest that these two polyketides might target an enzyme involved in coordination of the cell division cycle. Hence, they might, for instance, affect timing or spindle assembly mechanisms, leading to defects in chromosome segregation and/or spindle geometry 2018-12-10T00:00:00Z